Addition of grapes to both a standard and a high-fat Western pattern diet modifies hepatic and urinary metabolite profiles in the mouse
Diren Beyoğlu, Eun‐Jung Park, Adolfo Quiñones‐Lombraña, Asim Dave, Falguni Parande, John M. Pezzuto, Jeffrey R. Idle
Abstract
cytosolic glycolysis for mitochondrial ATP production. It is concluded that a grape diet reprogrammes gut microbiota metabolism, attenuates the hepatic oxidative stress of a high-fat diet and increases the efficiency of glucose utilization by the liver for energy production.
Topics & Concepts
MetaboliteUrinary systemWestern dietChemistryBiologyInternal medicineFood scienceEndocrinologyMedicineObesityDiet and metabolism studiesAdipose Tissue and MetabolismBiochemical effects in animals