Litcius/Paper detail

Structural mechanism of cGAS inhibition by the nucleosome

G.R. Pathare, Alexiane Decout, Selene Glück, Simone Cavadini, Kristina Makasheva, Ruud Hovius, Georg Kempf, Joscha Weiss, Zuzanna Kozicka, Baptiste Guey, Pauline Mélénec, Beat Fierz, Nicolas H. Thomä, Andrea Ablasser

2020Nature266 citationsDOIOpen Access PDF

Topics & Concepts

ChromatinNucleosomeHistoneCell biologyDNAChemistryInnate immune systemBiologyBiochemistryGeneticsImmune systeminterferon and immune responsesImmune Cell Function and InteractionImmune cells in cancer
Structural mechanism of cGAS inhibition by the nucleosome | Litcius