Accelerated aging with HIV occurs at the time of initial HIV infection
Elizabeth C. Breen, Mary E. Sehl, Roger Shih, Peter Langfelder, Ruibin Wang, Steve Horvath, Jay H. Bream, Priya Duggal, Jeremy Martinson, Steven M. Wolinsky, Otoniel Martı́nez-Maza, Christina M. Ramirez, Beth D. Jamieson
Abstract
). These longitudinal observations clearly demonstrate an early and substantial impact of HIV infection on the epigenetic aging process, and suggest a role for HIV itself in the earlier onset of clinical aging.
Topics & Concepts
Human immunodeficiency virus (HIV)VirologyComputational biologyMedicineBiologyHIV-related health complications and treatmentsHIV/AIDS Research and InterventionsHIV Research and Treatment