4. Insecticide-based approaches for dengue vector control
Scott A. Ritchie, Gregor J. Devine, Gonzalo M. Vazquez‐Prokopec, Audrey Lenhart, Pablo Manrique‐Saide, Thomas W. Scott
Abstract
Vector control is, and will continue to be, an essential component of dengue prevention programs, but in modern cities with highly mobile human populations and inadequate vector control infrastructure the global burden of dengue is increasing. This is in part, because effective vector control is difficult to achieve and sustain. Despite these challenges, past successes indicate that when it is carefully and thoroughly applied, mosquito control will reduce dengue, particularly when targeting Aedes aegypti in urban habitats. Herein we review insecticide-based approaches for dengue vector control. We conclude that to fight dengue it is important to use locally derived and adapted vector control tools and strategies. To achieve this, it is critical to thoroughly understand the local vector and its ecology, including its insecticide susceptibility. Available evidence indicates that most space sprays (both aerial and ground) are relatively ineffective unless they are repeatedly delivered inside homes where Ae. aegypti rests. Novel delivery methods have been developed to control Aedes vector populations using residual killing agents, including targeted indoor residual spraying, which shows promise for reducing dengue. Adulticiding for dengue prevention is most effective when it is conducted as part of an integrated vector management plan that includes source reduction and larviciding. Successful dengue prevention programs include a combination of tools and strategies (e.g. insecticides in combination with vaccines and non-insecticide-based interventions) that are applied with enhanced intersectorial and interdisciplinary cooperation and strong community engagement.