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Gene Regulatory Network Analysis and Engineering Directs Development and Vascularization of Multilineage Human Liver Organoids

Jeremy J. Velazquez, Ryan LeGraw, Farzaneh Moghadam, Yuqi Tan, Jacquelyn Kilbourne, Joseph C. Maggiore, Joshua Hislop, Silvia Liu, Davy Cats, Susana M. Chuva de Sousa Lopes, Christopher Plaisier, Patrick Cahan, Samira Kiani, Mo R. Ebrahimkhani

2020Cell Systems102 citationsDOIOpen Access PDF

Topics & Concepts

OrganoidBiologyCell biologyInduced pluripotent stem cellStem cellGene regulatory networkStromal cellHepatic stellate cellMorphogenesisCell fate determinationEmbryonic stem cellGene expressionGeneTranscription factorGeneticsCancer researchEndocrinologyLiver physiology and pathologyPluripotent Stem Cells ResearchRenal and related cancers
Gene Regulatory Network Analysis and Engineering Directs Development and Vascularization of Multilineage Human Liver Organoids | Litcius