Structure-directed identification of pyridine-2-methylamine derivatives as MmpL3 inhibitors for use as antitubercular agents
Yu Wen, Shichun Lun, Yuxue Jiao, Wei Zhang, Ting Liu, Fan Yang, Jie Tang, William R. Bishai, Li-Fang Yu
Topics & Concepts
ChemistryMethylamineStereochemistryPyridineBiochemistryMedicinal chemistryTuberculosis Research and EpidemiologyCancer therapeutics and mechanismsHIV/AIDS drug development and treatment