A RUNX–CBFβ-driven enhancer directs the Irf8 dose-dependent lineage choice between DCs and monocytes
Koichi Murakami, Haruka Sasaki, Akira Nishiyama, Daisuke Kurotaki, Wataru Kawase, Tatsuma Ban, Jun Nakabayashi, Satoko Kanzaki, Yoichi Sekita, Hideaki Nakajima, Keiko Ozato, Tohru Kimura, Tomohiko Tamura
Topics & Concepts
IRF8EnhancerTranscription factorBiologyCell biologyMyeloidProgenitor cellHaematopoiesisCellular differentiationMonocyteStem cellImmunologyGeneticsGeneImmunotherapy and Immune ResponsesImmune cells in cancerEpigenetics and DNA Methylation