Protective effect of astaxanthin against La2O3 nanoparticles induced neurotoxicity by activating PI3K/AKT/Nrf-2 signaling in mice
Yuan Lu, Yun-Hua Qu, Qingzhao Li, Tianyang An, Zhenfei Chen, Yajing Chen, Xuenan Deng, Disi Bai
Topics & Concepts
NeurotoxicityOxidative stressChemistryProtein kinase BNeuroinflammationNeuroprotectionPharmacologyPI3K/AKT/mTOR pathwaySOD1Signal transductionBiochemistrySuperoxide dismutaseBiologyInflammationImmunologyToxicityOrganic chemistryNanoparticles: synthesis and applicationsAnesthesia and Neurotoxicity ResearchAntioxidant Activity and Oxidative Stress