Brainstem circuits encoding start, speed, and duration of swimming in adult zebrafish
Eva M. Berg, Leander Mrowka, Maria Bertuzzi, David Madrid, Laurence D. Picton, Abdeljabbar El Manira
Abstract
neuron ablation impaired fast swimming. Our results provide mechanistic insights into how separate brainstem subpopulations implement flexible locomotor commands. These two brainstem command subpopulations are suitably organized to integrate environmental cues and hence generate flexible swimming movements to match the animal's behavioral needs.
Topics & Concepts
NeuroscienceBrainstemGlutamatergicZebrafishElectrophysiologyCalcium imagingBiological neural networkNeuronBiologyMedial longitudinal fasciculusPremovement neuronal activityGlutamate receptorMidbrainMedicineCentral nervous systemReceptorInternal medicineBiochemistryCalciumGeneZebrafish Biomedical Research ApplicationsNeural dynamics and brain functionPhysiological and biochemical adaptations