Litcius/Paper detail

High-risk human-caused pathogen exposure events from 1975-2016

David Manheim, Gregory W. Lewis

2022F1000Research24 citationsDOIOpen Access PDF

Abstract

<ns3:p>Biological agents and infectious pathogens have the potential to cause very significant harm, as the natural occurrence of disease and pandemics makes clear. As a way to better understand the risk of Global Catastrophic Biological Risks due to human activities, rather than natural sources, this paper reports on a dataset of 71 incidents involving either accidental or purposeful exposure to, or infection by, a highly infectious pathogenic agent.</ns3:p> <ns3:p/> <ns3:p>There has been significant effort put into both reducing the risk of purposeful spread of biological weapons, and biosafety intended to prevent the exposure to, or release of, dangerous pathogens in the course of research. Despite these efforts, there are incidents of various types that could potentially be controlled or eliminated by different lab and/or bioweapon research choices and safety procedures.</ns3:p> <ns3:p/> <ns3:p>The dataset of events presented here was compiled during a project conducted in 2019 to better understand biological risks from anthropic sources. The events which are listed are unrelated to clinical treatment of naturally occurring outbreaks, and are instead entirely the result of human decisions and mistakes. While the events cover a wide range of cases, the criteria used covers a variety of events previously scattered across academic, policy, and other unpublished or not generally available sources.</ns3:p>

Topics & Concepts

BiosafetyInfectious disease (medical specialty)HarmPandemicOutbreakRisk analysis (engineering)BiologyMedicineDiseaseBiotechnologyVirologyCoronavirus disease 2019 (COVID-19)PathologyLawPolitical scienceBacillus and Francisella bacterial researchViral Infections and Outbreaks ResearchZoonotic diseases and public health