Recent advances in clinical trials targeting the kynurenine pathway
Ananda Staats Pires, Gayathri Sundaram, Benjamin Heng, Shivani Krishnamurthy, Bruce J. Brew, Gilles J. Guillemin
Topics & Concepts
Quinolinic acidKynurenine pathwayKynurenineKynurenic acidNeuroprotectionMultiple sclerosisIndoleamine 2,3-dioxygenaseNeurotoxicityImmune systemPharmacologyInflammationNicotinamide adenine dinucleotideBiologyChemistryMedicineBiochemistryAmino acidTryptophanImmunologyEnzymeNAD+ kinaseInternal medicineToxicityTryptophan and brain disordersStress Responses and CortisolBipolar Disorder and Treatment