Synthesis and biological evaluation of 1,2,4-oxadiazole core derivatives as potential neuroprotectants against acute ischemic stroke
Jinguo Shi, Yang Wang, Jianwen Chen, Yaoqiang Lao, Ping Huang, Liping Liao, Caibao Jiang, Xinhua Li, Jin Wen, Shujia Zhou, Jingxia Zhang
Topics & Concepts
NeuroprotectionPharmacologyReactive oxygen speciesStroke (engine)In vivoChemistryAntioxidantIschemiaOxidative stressMedicineBiochemistryBiologyInternal medicineMechanical engineeringBiotechnologyEngineeringGenomics, phytochemicals, and oxidative stressFree Radicals and AntioxidantsNeuroinflammation and Neurodegeneration Mechanisms