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Lysine acylation using conjugating enzymes for site-specific modification and ubiquitination of recombinant proteins

Raphael Hofmann, Gaku Akimoto, Thomas Wucherpfennig, Cathleen Zeymer, Jeffrey W. Bode

2020Nature Chemistry75 citationsDOI

Topics & Concepts

LysineChemistryBiochemistryEnzymeAcylationPeptideResidue (chemistry)UbiquitinProtein engineeringUbiquitin-conjugating enzymeRecombinant DNAConjugateUbiquitinsLinkerAmino acidUbiquitin ligaseCatalysisGeneMathematical analysisComputer scienceMathematicsOperating systemPeptidase Inhibition and AnalysisBiochemical and Structural CharacterizationUbiquitin and proteasome pathways
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