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Idebenone ameliorates statin-induced myotoxicity in atherosclerotic ApoE−/− mice by reducing oxidative stress and improving mitochondrial function

Wenfei Yu, Wenjing Wu, Dandan Zhao, Rui Zhang, Kai Shao, Haoyang Liu, Chuanzhu Yan, Pengfei Lin

2024Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease10 citationsDOI

Topics & Concepts

IdebenoneSimvastatinStatinOxidative stressPharmacologyMyotoxinMedicineMitochondrionChemistryBiochemistryInternal medicinePhospholipase A2EnzymeMitochondrial Function and PathologyCoenzyme Q10 studies and effectsLipoproteins and Cardiovascular Health
Idebenone ameliorates statin-induced myotoxicity in atherosclerotic ApoE−/− mice by reducing oxidative stress and improving mitochondrial function | Litcius