Direct quantitation of free, encapsulated, total doxorubicin and doxorubicinol in stabilized frozen human plasma to support a BE study of liposomal doxorubicin
Yuhuan Ji, Xueyuan Zhang, Jinzhi Liu, Yu Chen, Min Meng, Chunlei Li, Laixin Wang
Topics & Concepts
DoxorubicinChemistryChromatographyBioequivalencePharmacokineticsLiposomePharmacologyChemotherapyBiochemistrySurgeryMedicineMass Spectrometry Techniques and ApplicationsChemotherapy-induced cardiotoxicity and mitigationLung Cancer Research Studies