p53 drives necroptosis via downregulation of sulfiredoxin and peroxiredoxin 3
Sergio Rius‐Pérez, Salvador Pérez, Michel B. Tolédano, Juan Sastre
Abstract
and p53 that downregulates sulfiredoxin and peroxiredoxin 3 leading to necroptosis in inflammation and obesity.
Topics & Concepts
NecroptosisDownregulation and upregulationBiologyProgrammed cell deathApoptosisBiochemistryGeneEndoplasmic Reticulum Stress and Diseaseinterferon and immune responsesCell death mechanisms and regulation