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Serological tests for COVID‐19: Potential opportunities

Marcarious M. Tantuoyir, Nima Rezaei

2020Cell Biology International40 citationsDOIOpen Access PDF

Abstract

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a novel betacoronavirus, caused a pandemic leading to a standstill of nearly all global activities. There are some controversies on the production of specific immunoglobulin M (IgM) and IgG antibodies after the infection with SARS-CoV-2. This paper seeks to elaborate on the potential application of IgM and IgG antibodies and the viral antigens for the diagnosis and the course of the disease as well as the recurrence of positive nucleic acid tests after discharge.

Topics & Concepts

SerologyCoronavirus disease 2019 (COVID-19)AntibodySevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)VirologyPandemicImmunologyCoronavirusBetacoronavirus2019-20 coronavirus outbreakAntigenMedicineImmunoglobulin MImmunoglobulin GDiseaseInfectious disease (medical specialty)PathologyOutbreakSARS-CoV-2 and COVID-19 ResearchCOVID-19 Clinical Research StudiesSARS-CoV-2 detection and testing