Cancer‐associated fibroblasts secrete hypoxia‐induced serglycin to promote head and neck squamous cell carcinoma tumor cell growth in vitro and in vivo by activating the Wnt/β-catenin pathway
Junqi Xie, Xiaofeng Qi, Yufeng Wang, Xiteng Yin, Wenguang Xu, Shengwei Han, Yu Cai, Wei Han
Topics & Concepts
Head and neck squamous-cell carcinomaWnt signaling pathwaySecretionCateninIn vivoCancer researchIn vitroCell growthCancerHypoxia (environmental)Cell cultureCellBasal cellMedicineHead and neck cancerChemistryPathologyBiologyInternal medicineCell biologySignal transductionBiochemistryOrganic chemistryGeneticsBiotechnologyOxygenCancer Cells and MetastasisCancer, Hypoxia, and MetabolismProteoglycans and glycosaminoglycans research