Targeting DNA damage response pathways in cancer
Florian J. Groelly, Matthew Fawkes, Rebecca A. Dagg, Andrew N. Blackford, Madalena Tarsounas
Topics & Concepts
Homologous recombinationDNA repairDNA damageGenome instabilityPoly ADP ribose polymeraseSynthetic lethalityBiologyCancer researchCancerGeneMutationGeneticsDNACancer cellPolymeraseComputational biologyPARP inhibition in cancer therapyDNA Repair MechanismsCancer-related Molecular Pathways