Replacing methanol with azeotropic ethanol as the co-solvent for improved chiral separations with supercritical fluid chromatography (SFC)
Daipayan Roy, M. Farooq Wahab, Mohsen Talebi, Daniel W. Armstrong
Abstract
Using azeoptropic ‘190 proof’ ethanol eliminates the use of methanol in chiral super/subcritical fluid chromatography.
Topics & Concepts
Supercritical fluid chromatographyChemistrySupercritical fluidMethanolEthanolSolventChromatographyOrganic chemistryHigh-performance liquid chromatographyAnalytical Chemistry and ChromatographyChromatography in Natural ProductsCrystallization and Solubility Studies