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Prognostic Value of the Systemic Immune Inflammation Index after Thoracic Endovascular Aortic Repair in Patients with Type B Aortic Dissection

Yufei Zhao, Junhao Jiang, Ye Yuan, Xiaolong Shu, Enci Wang, Weiguo Fu, Lixin Wang

2023Disease Markers13 citationsDOIOpen Access PDF

Abstract

The study aimed at investigating the association between postoperative inflammatory scores and aorta-related adverse events (AAEs) after thoracic endovascular aortic repair (TEVAR) for patients with type B aortic dissection (TBAD). This single-centre, retrospective cohort included all patients who underwent TEVAR for TBAD between November 2016 and November 2020 at a university hospital. The risk factors for AAEs were analyzed by Cox proportional hazards model regression. Prediction accuracy was assessed using the area under the receiver operating characteristic curves. This study included 186 patients with a mean age of 58.5 years and a median follow-up period of 26 months. A total of 68 patients developed AAEs. Age and postoperative systemic immune inflammation index (SII) (&gt;2893) were associated with post-TEVAR AAEs (hazard ratio (HR) 1.03, <a:math xmlns:a="http://www.w3.org/1998/Math/MathML" id="M1"> <a:mi>p</a:mi> <a:mo>=</a:mo> <a:mn>0.003</a:mn> </a:math> ; HR 1.88, <c:math xmlns:c="http://www.w3.org/1998/Math/MathML" id="M2"> <c:mi>p</c:mi> <c:mo>=</c:mo> <c:mn>0.043</c:mn> </c:math> , respectively). Increased postoperative SII and age are independent risk factors for AAE post-TEVAR in patients with TBAD.

Topics & Concepts

MedicineAortic dissectionSystemic inflammationAortic repairInflammationAortic aneurysmImmune systemCardiologyThoracic aortic aneurysmSurgeryInternal medicineAortaRadiologyImmunologyAortic Disease and Treatment ApproachesAortic aneurysm repair treatmentsInfectious Aortic and Vascular Conditions
Prognostic Value of the Systemic Immune Inflammation Index after Thoracic Endovascular Aortic Repair in Patients with Type B Aortic Dissection | Litcius