Carbon Monoxide and Nitric Oxide as Examples of the Youngest Class of Transmitters
Alicja Nowaczyk, Magdalena Kowalska, Jacek Nowaczyk, Grzegorz Grześk
Abstract
The year 2021 is the 100th anniversary of the confirmation of the neurotransmission phenomenon by Otto Loewi. Over the course of the hundred years, about 100 neurotransmitters belonging to many chemical groups have been discovered. In order to celebrate the 100th anniversary of the confirmation of neurotransmitters, we present an overview of the first two endogenous gaseous transmitters i.e., nitric oxide, and carbon monoxide, which are often termed as gasotransmitters.
Topics & Concepts
Nitric oxideCarbon monoxideNeurotransmissionChemistryNeuroscienceBiologyBiochemistryOrganic chemistryReceptorCatalysisHeme Oxygenase-1 and Carbon MonoxideHemoglobin structure and functionNeuroscience of respiration and sleep