Delivery of mRNA vaccines and anti-PDL1 siRNA through non-invasive transcutaneous route effectively inhibits tumor growth
Kaili Wang, Xiaoyun Wang, Di Jiang, Yifei Pei, Zhe Wang, Xiaojun Zhou, Jinglei Wu, Xiumei Mo, Hongsheng Wang
Topics & Concepts
TransdermalMessenger RNAIn vivoImmune systemCancer researchTransfectionApoptosisSmall interfering RNAMelanomaChemistryBiologyImmunologyPharmacologyCell cultureBiochemistryBiotechnologyGeneGeneticsImmunotherapy and Immune ResponsesRNA Interference and Gene DeliveryExtracellular vesicles in disease