Prospectives and challenges of nano-tailored biomaterials-assisted biological molecules delivery for tissue engineering purposes
Mohammad El-Nablaway, Fatema Rashed, Ehab S. Taher, Tarek Foda, Ahmed Abdeen, Mohamed Abdo, Liana Fericean, Ioan Bănățean-Dunea, Ostan Mihaela, Ştefania Dinu, Cucui-Cozma Alexandru, Noha Taymour, Nourelhuda A. Mohammed, Mohamed El-Sherbiny, Ateya Megahed Ibrahim, Donia Elsaid Fathi Zaghamir, Gamal Abdel Nasser Atia
Abstract
Nano carriers have gained more attention for their possible medical and technological applications. Tailored nanomaterials can transport medications efficiently to targeted areas and allow for sustained medication discharge, reducing undesirable toxicities while boosting curative effectiveness. Nonetheless, transitioning nanomedicines from experimental to therapeutic applications has proven difficult, so different pharmaceutical incorporation approaches in nano scaffolds are discussed. Then numerous types of nanobiomaterials implemented as carriers and their manufacturing techniques are explored. This article is also supported by various applications of nanobiomaterials in the biomedical field. • Nano-inspired platforms have the potential to revolutionize drug delivery and tissue engineering. • These platforms offer advantages such as targeted drug delivery, improved bioavailability, and enhanced tissue regeneration. • Strategies for drug release from these platforms include diffusion, degradation, and stimuli-responsive release. • Nano-inspired platforms in tissue engineering: 3D scaffolds and magnetic nanoparticles for hyperthermia • Future advancements: Nanorobots for precise drug delivery and smart materials for tissue engineering.