Litcius/Paper detail

Biofortified tomatoes provide a new route to vitamin D sufficiency

Jie Li, Aurelia Scarano, Néstor Mora González, Fabio D’Orso, Yajuan Yue, Krisztián Németh, Gerhard Saalbach, Lionel Hill, Carlo Martins, Rolando Morán, Angelo Santino, Cathie Martin

2022Nature Plants155 citationsDOIOpen Access PDF

Abstract

Abstract Poor vitamin D status is a global health problem; insufficiency underpins higher risk of cancer, neurocognitive decline and all-cause mortality. Most foods contain little vitamin D and plants are very poor sources. We have engineered the accumulation of provitamin D 3 in tomato by genome editing, modifying a duplicated section of phytosterol biosynthesis in Solanaceous plants, to provide a biofortified food with the added possibility of supplement production from waste material.

Topics & Concepts

BiofortificationVitaminBiotechnologyPhytosterolNeurocognitiveBiologyMalnutritionFood processingGenomeEnvironmental healthNatural resource economicsFood scienceMedicineGeneBiochemistryEconomicsPathologyCognitionNeuroscienceMicronutrientVitamin D Research Studies