Multifunctional injectable hydrogel system as a mild photothermal-assisted therapeutic platform for programmed regulation of inflammation and osteo-microenvironment for enhanced healing of diabetic bone defects <i>in situ</i>
Yufan Zhu, Huifan Liu, Pin Wu, Yun Chen, Zhouming Deng, Lin Cai, Minhao Wu
Abstract
Overall, the constructed multifunctional injectable hydrogel system has emerged as a promising therapeutic candidate for addressing complex bone-related challenges by remodeling the disordered immune microenvironment and expediting the bone healing process.
Topics & Concepts
InflammationPhotothermal therapyBone healingIn situBiomedical engineeringMedicineSelf-healing hydrogelsMaterials scienceChemistryNanotechnologyImmunologySurgeryOrganic chemistryPolymer chemistryNanoplatforms for cancer theranosticsMesenchymal stem cell researchOsteoarthritis Treatment and Mechanisms