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A formal [4 + 1] cycloaddition reaction of Baylis–Hillman bromides with sulfur ylides: facile access to α-alkenyl lactones

Ting‐Bi Hua, Yuhong Ma, Xiaoyu He, Long Wang, Jiaying Yan, Qing‐Qing Yang

2022Organic Chemistry Frontiers12 citationsDOI

Abstract

A formal [4 + 1] cycloaddition reaction of Baylis–Hillman adducts with sulfur ylides has been developed for the first time.

Topics & Concepts

ChemistryCycloadditionAdductSulfurOrganic chemistryMedicinal chemistryCatalysisSynthesis and Catalytic ReactionsOrganic Chemistry Cycloaddition ReactionsCyclopropane Reaction Mechanisms
A formal [4 + 1] cycloaddition reaction of Baylis–Hillman bromides with sulfur ylides: facile access to α-alkenyl lactones | Litcius