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Rapid induction of antigen-specific CD4+ T cells is associated with coordinated humoral and cellular immunity to SARS-CoV-2 mRNA vaccination

Mark M. Painter, Divij Mathew, Rishi R. Goel, Sokratis A. Apostolidis, Ajinkya Pattekar, Oliva Kuthuru, Amy E. Baxter, Ramin S. Herati, Derek A. Oldridge, Sigrid Gouma, Philip Hicks, Sarah Dysinger, Kendall A. Lundgreen, Leticia Kuri-Cervantes, Sharon Adamski, Amanda Hicks, Scott W. Korte, Josephine R. Giles, Madison E. Weirick, Christopher M. McAllister, Jeanette Dougherty, Sherea Long, Kurt D’Andrea, Jacob T. Hamilton, Michael R. Betts, Paul Bates, Scott E. Hensley, Alba Grifoni, Daniela Weiskopf, Alessandro Sette, Allison R. Greenplate, E. John Wherry

2021Immunity520 citationsDOIOpen Access PDF

Topics & Concepts

BiologyVirologyVaccinationImmunityAntigenHumoral immunityImmunologyMessenger RNASevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Immune systemCoronavirus disease 2019 (COVID-19)GeneMedicineGeneticsInfectious disease (medical specialty)PathologyDiseaseSARS-CoV-2 and COVID-19 ResearchImmunotherapy and Immune ResponsesCOVID-19 Clinical Research Studies
Rapid induction of antigen-specific CD4+ T cells is associated with coordinated humoral and cellular immunity to SARS-CoV-2 mRNA vaccination | Litcius