TLR2 activation promotes tumour growth and associates with patient survival and chemotherapy response in pancreatic ductal adenocarcinoma
Joanne Lundy, Linden J. Gearing, Hugh Gao, Alison C. West, Louise McLeod, Virginie Deswaerte, Liang Yu, Sean Porazinski, Marina Pajic, Paul J. Hertzog, Daniel Croagh, Brendan J. Jenkins
Topics & Concepts
BiologyPancreatic cancerTLR2Cancer researchInnate immune systemGemcitabineTranscriptomeAdenocarcinomaImmune systemPancreasGene expression profilingToll-like receptorPancreatic ductal adenocarcinomaTargeted therapyOncologyImmunologyInternal medicineChemotherapyCancerMedicineGeneGene expressionBiochemistryGeneticsPancreatic and Hepatic Oncology ResearchCancer Immunotherapy and BiomarkersImmune cells in cancer