EGFR-TNFR1 pathway in endothelial cell facilitates acute lung injury by NF-κB/MAPK-mediated inflammation and RIP3-dependent necroptosis
Huiling Zhang, Xuedi Zhang, Chunxiu Ling, Change Liu, Shaodong Hua, Ziying Xiong, Huimin Zhao, Qiushuang Feng, Zhichun Feng, Jing Tang, Xiaoyang Hong
Topics & Concepts
NecroptosisInflammationTumor necrosis factor alphaTRAF2Epidermal growth factor receptorTumor necrosis factor receptor 1Cancer researchMAPK/ERK pathwayTRADDSignal transductionCell biologyBiologyImmunologyReceptorProgrammed cell deathMedicineDeath domainApoptosisInternal medicineBiochemistryTumor necrosis factor receptorCell death mechanisms and regulationImmune Response and InflammationInflammasome and immune disorders