Presence of Extracellular Alpha-Synuclein Aggregates Trigger Astrocytic Degeneration Through Enhanced Membrane Rigidity and Deregulation of Store-Operated Calcium Entry (SOCE) into the Endoplasmic Reticulum
Aishwarya Raj, Roon Banerjee, Rashmi Santhoshkumar, Chandrasekhar Sagar, Indrani Datta
Topics & Concepts
Cell biologyExtracellularEndoplasmic reticulumAstrocyteLipid raftChemistryIntracellularBiologyBiochemistrySignal transductionEndocrinologyCentral nervous systemParkinson's Disease Mechanisms and TreatmentsRestless Legs Syndrome ResearchNerve injury and regeneration