Resolving the deceptive isoform and complex selectivity of HDAC1/2 inhibitors
N. Connor Payne, Ralph Mazitschek
Topics & Concepts
CorepressorEpigeneticsHistoneHDAC1Histone deacetylaseGene isoformComputational biologyChromatinChemistrySmall moleculeSelectivityBiologyBiochemistryDNAGeneGene expressionRepressorCatalysisHistone Deacetylase Inhibitors ResearchProtein Degradation and InhibitorsPeptidase Inhibition and Analysis