A microenvironment-sensitive red emissive probe with a large Stokes shift for specific recognition and quantification of serum albumin in complex biofluids and live cells
Mihir Sasmal, Abu Saleh Musha Islam, Dolan Moni, Atul Katarkar, Mahammad Ali
Abstract
) in aqueous solutions, which is significantly lower than the normal level of HSA in healthy urine and blood serum, indicating its high sensitivity. DCI-MIN has the ability to exhibit useful applications, including the detection and quantification of HSA concentration in complex biofluids (human urine and blood samples) as well as the imaging of serum albumin in living cells.
Topics & Concepts
Stokes shiftAlbuminChemistryOptoelectronicsMaterials scienceBiochemistryLuminescenceProtein Interaction Studies and Fluorescence AnalysisLipid Membrane Structure and BehaviorAdvanced Fluorescence Microscopy Techniques