Electrophotoredox cerium-catalyzed decarboxylative radical cyclization cascade for the synthesis of alkylated benzimidazo-fused isoquinolinones
Meng Wang, Dehui Wang, Kun Xu, Cheng‐Chu Zeng
Abstract
We report an electrophotoredox cerium-catalyzed LMCT strategy to incorporate carboxylic acids into radical cyclization cascades. This protocol provides a solution to address the challenges in alkylated benzimidazo-fused isoquinolinone synthesis.
Topics & Concepts
CeriumChemistryAlkylationCatalysisRadical cyclizationCascadeCombinatorial chemistryOrganic chemistryChromatographyRadical Photochemical ReactionsCatalytic C–H Functionalization MethodsOxidative Organic Chemistry Reactions