Binding of LAG-3 to stable peptide-MHC class II limits T cell function and suppresses autoimmunity and anti-cancer immunity
Takumi Maruhashi, Daisuke Sugiura, Il‐mi Okazaki, Kenji Shimizu, Takeo K. Maeda, Jun Ikubo, Harunori Yoshikawa, Katsumi Maenaka, Naozumi Ishimaru, Hidetaka Kosako, Tatsuya Takemoto, Taku Okazaki
Topics & Concepts
BiologyAutoimmunityMajor histocompatibility complexImmunityReceptorCell biologyImmunologyLigand (biochemistry)Immune systemCancer researchBiochemistryCancer Immunotherapy and BiomarkersImmune Cell Function and InteractionPhagocytosis and Immune Regulation