Oxidase Mimic Graphdiyne for Efficient Superoxide Generation in Wide pH Ranges
Yu Gu, Cunxia Fan, Xijuan Hao, Fangxin Hu, Chunmei Zhang, Hongbin Yang, Chang Ming Li, Chunxian Guo
Abstract
Abstract Great effort has been made in exploring techniques and catalysts for O 2 •− production but they always work efficiently in either acidic or base environment. Presented here is the design of a unique oxidase mimic catalyst comprising self‐assembled hemin molecules on graphdiyne (hemin/GDY) for efficient O 2•− generation in wide pH ranges. Hemin molecules anchor uniformly across the carbon frame of GDY to enable atomic distribution of the active metal sites, delivering a O 2 •− production rate of 35.7 and 2.3 times than that of hemin and hemin/graphene, respectively. In particular, hemin/GDY can efficiently produce O 2 •− in acidic, alkaline, and neutral environments, delivering a wide pH behavior. Its oxidase mimic ability is demonstrated for sensing glutathione molecules in cell assays, exhibiting high selectivity, long linear range. This work opens a promising design strategy toward efficient oxidase mimic catalysts for various applications.