Mannose-functionalized antigen nanoparticles for targeted dendritic cells, accelerated endosomal escape and enhanced MHC-I antigen presentation
Mengyue Pei, Rong Xu, Chuangnian Zhang, Xiaoli Wang, Chen Li, Yunzhang Hu
Topics & Concepts
AntigenCross-presentationAntigen presentationAntigen-presenting cellMannoseEndosomeChemistryMannose receptorImmunotherapyDendritic cellCell biologyMajor histocompatibility complexT cellImmune systemMHC class IImmunologyBiologyIn vitroCellMacrophageBiochemistryImmunotherapy and Immune ResponsesNanoplatforms for cancer theranosticsRNA Interference and Gene Delivery