Split-luciferase complementary assay of NLRP3 PYD-PYD interaction indicates inflammasome formation during inflammation
Mohsen Isazadeh, Mojdeh Amandadi, Farnaz Haghdoust, Shima Lotfollazadeh, Mar Orzáez, Saman Hosseinkhani
Topics & Concepts
InflammasomePyrin domainLuciferaseChemistryCell biologyComplementationProtein-fragment complementation assayInnate immune systemIn vitroEffectorReceptorBiophysicsTransfectionBiologyBiochemistryMutantGeneInflammasome and immune disordersHeme Oxygenase-1 and Carbon MonoxideIon Channels and Receptors