Membrane active 7-thiazoxime quinolones as novel DNA binding agents to decrease the genes expression and exert potent anti-methicillin-resistant Staphylococcus aureus activity
Jinping Chen, Narsaiah Battini, Mohammad Fawad Ansari, Cheng‐He Zhou
Topics & Concepts
DNA gyraseChemistryCiprofloxacinQuinoloneStaphylococcus aureusMicrobiologyAntibacterial agentAntibacterial activityAntimicrobialTopoisomerase IVAntibioticsBacteriaGeneEscherichia coliBiochemistryBiologyGeneticsOrganic chemistryPhenothiazines and Benzothiazines Synthesis and ActivitiesSynthesis and Biological EvaluationCancer therapeutics and mechanisms