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RAF1 kinase activity is dispensable for KRAS/p53 mutant lung tumor progression

Manuel Sanclemente, Patricia Nieto, Sara García‐Alonso, Fernando Fernández-García, Laura Esteban-Burgos, Carmen Guerra, Matthias Drosten, Eduardo Caleiras, Jorge L. Martı́nez-Torrecuadrada, David Santamarı́a, Mónica Musteanu, Mariano Barbacid

2021Cancer Cell36 citationsDOIOpen Access PDF

Topics & Concepts

KRASMutantCancer researchKinaseMutationBiologyCell biologyGeneGeneticsProtein Degradation and InhibitorsUbiquitin and proteasome pathwaysMelanoma and MAPK Pathways
RAF1 kinase activity is dispensable for KRAS/p53 mutant lung tumor progression | Litcius