Suppression of the SLC7A11/glutathione axis causes ferroptosis and apoptosis and alters the mitogen-activated protein kinase pathway in nasopharyngeal carcinoma
Haihua Wang, Songqing Fan, Yuting Zhan, Shuping Peng, Weiyuan Wang
Topics & Concepts
GlutathioneMAPK/ERK pathwayCystineApoptosisSorafenibReactive oxygen speciesCancer researchNasopharyngeal carcinomaKinaseChemistryProtein kinase ACell biologyBiologyBiochemistryMedicineInternal medicineRadiation therapyHepatocellular carcinomaCysteineEnzymeEpigenetics and DNA MethylationFerroptosis and cancer prognosisRNA modifications and cancer