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TCF-1 controls Treg cell functions that regulate inflammation, CD8+ T cell cytotoxicity and severity of colon cancer

Abu Osman, Bingyu Yan, Ying Li, Kevin D. Pavelko, Jasmine Quandt, Abdulrahman Saadalla, Mahendra Pal Singh, Majid Kazemian, Fotini Gounari, Khashayarsha Khazaie

2021Nature Immunology83 citationsDOIOpen Access PDF

Topics & Concepts

FOXP3Cytotoxic T cellT cellInflammationBiologyCancer researchImmunologyCD8Transcription factorCellCell biologyImmune systemGeneIn vitroGeneticsBiochemistryImmune Cell Function and InteractionT-cell and B-cell ImmunologyAtherosclerosis and Cardiovascular Diseases
TCF-1 controls Treg cell functions that regulate inflammation, CD8+ T cell cytotoxicity and severity of colon cancer | Litcius