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The Compact Macronuclear Genome of the Ciliate Halteria grandinella: A Transcriptome-Like Genome with 23,000 Nanochromosomes

Weibo Zheng, Chundi Wang, Michael Lynch, Shan Gao

2021mBio44 citationsDOIOpen Access PDF

Abstract

How to achieve protein diversity by genome and transcriptome processing is essential for organismal complexity and adaptation. The present work identifies that the macronuclear genome of Halteria grandinella , a cosmopolitan unicellular eukaryote, is composed almost entirely of gene-sized nanochromosomes with extremely short nongenic regions.

Topics & Concepts

GenomeTranscriptomeBiologyEukaryoteGeneAdaptation (eye)CiliateComputational biologyGeneticsGene expressionNeuroscienceProtist diversity and phylogenyMicrobial Community Ecology and PhysiologyGenomics and Phylogenetic Studies
The Compact Macronuclear Genome of the Ciliate Halteria grandinella: A Transcriptome-Like Genome with 23,000 Nanochromosomes | Litcius