A biomimetic hierarchical small intestinal submucosa–chitosan sponge/chitosan hydrogel scaffold with a micro/nano structure for dural repair
Jingxi Wang, Kun Li, Junwei Xu, Meili Liu, Ping Li, Xiaoming Li, Yubo Fan
Abstract
subcutaneous implantation in rats. Thus, the biomimetic hierarchical small intestinal submucosa-chitosan sponge/chitosan hydrogel scaffold with micro/nano structure simulates the structure of the natural dura mater and possesses properties with excellent performance, which has high practical value for dural repair.
Topics & Concepts
ChitosanBiocompatibilityMaterials scienceNanofiberScaffoldTissue engineeringSelf-healing hydrogelsSubmucosaBilayerBiomedical engineeringBiophysicsNanotechnologyChemistryPolymer chemistryMembraneSurgeryMedicineOrganic chemistryBiochemistryBiologyMetallurgyTissue Engineering and Regenerative MedicineHead and Neck Surgical OncologyElectrospun Nanofibers in Biomedical Applications