Cytotoxic CD4+ T cells eliminate senescent cells by targeting cytomegalovirus antigen
Tatsuya Hasegawa, Tomonori Oka, Heehwa G. Son, Valeria S. Oliver-García, Marjan Azin, Thomas Eisenhaure, David Lieb, Nir Hacohen, Shadmehr Demehri
Topics & Concepts
Cytotoxic T cellBiologyHuman cytomegalovirusFibroblastImmunologyAntigenImmune systemCTL*Human leukocyte antigenVirologyCancer researchVirusCD8Cell cultureIn vitroGeneticsBiochemistryCytomegalovirus and herpesvirus researchImmune Cell Function and InteractionTelomeres, Telomerase, and Senescence