Fungal Endocarditis: Pathophysiology, Epidemiology, Clinical Presentation, Diagnosis, and Management
George R. Thompson, Jeffrey D. Jenks, John W. Baddley, James S. Lewis, Matthias Egger, Ilan S. Schwartz, Johannes Boyer, Thomas F. Patterson, Sharon C.‐A. Chen, Peter G. Pappas, Martin Hoenigl
Abstract
Fungal endocarditis accounts for 1% to 3% of all infective endocarditis cases, is associated with high morbidity and mortality (>70%), and presents numerous challenges during clinical care. Candida spp. are the most common causes of fungal endocarditis, implicated in over 50% of cases, followed by Aspergillus and Histoplasma spp. Important risk factors for fungal endocarditis include prosthetic valves, prior heart surgery, and injection drug use.
Topics & Concepts
EndocarditisMedicineEpidemiologyInfective endocarditisPathophysiologyMycosisIntensive care medicineSurgeryInternal medicineAntifungal resistance and susceptibilityInfective Endocarditis Diagnosis and ManagementFungal Infections and Studies