Flavonoids in Ampelopsis grossedentata as covalent inhibitors of SARS-CoV-2 3CLpro: Inhibition potentials, covalent binding sites and inhibitory mechanisms
Yuan Xiong, Guanghao Zhu, Yani Zhang, Qing Hu, Haonan Wang, Haonan Yu, Xiaoya Qin, Xiao‐Qing Guan, Yan‐Wei Xiang, Hui Tang, Guang‐Bo Ge
Topics & Concepts
MyricetinChemistryBiochemistryCovalent bondFlavonoidInhibitory postsynaptic potentialPolyphenolKaempferolBiologyAntioxidantOrganic chemistryNeuroscienceComputational Drug Discovery MethodsSynthesis and biological activityFlavonoids in Medical Research