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Allosteric regulation by membranes and hydrophobic subsites in phospholipase A2 enzymes determine their substrate specificity

Edward A. Dennis

2022Journal of Biological Chemistry21 citationsDOIOpen Access PDF

Abstract

specificity and inhibition potency with molecular structure and physiological function.

Topics & Concepts

Allosteric regulationBiochemistryEnzymePhospholipidPhospholipasePhospholipase A2LipidomicsChemistryBiologyMembraneProtein Kinase Regulation and GTPase SignalingPeroxisome Proliferator-Activated ReceptorsMitochondrial Function and Pathology
Allosteric regulation by membranes and hydrophobic subsites in phospholipase A2 enzymes determine their substrate specificity | Litcius