The natural product dehydrocurvularin induces apoptosis of gastric cancer cells by activating PARP-1 and caspase-3
Huibin Xu, Xiaoman Shen, Xiangke Li, Xiaohui Yang, Chuan Chen, Du‐Qiang Luo
Topics & Concepts
Poly ADP ribose polymerasePARP inhibitorApoptosisOlaparibApoptosis-inducing factorCancer researchCaspase 3BiologyMolecular biologyNAD+ kinaseCancer cellChemistryCaspaseCell biologyProgrammed cell deathBiochemistryCancerPolymeraseDNAEnzymeGeneticsPARP inhibition in cancer therapyToxin Mechanisms and ImmunotoxinsCell death mechanisms and regulation