Nanodot-doped peptide hydrogels for antibacterial phototherapy and wound healing
Xuan Wang, Lin Qiu, Cheng Wang, Zihan Gao, Shuwen Zhou, Peng‐Fei Cui, Pengju Jiang, Huaanzi Hu, Xinye Ni, Xuancheng Du, Jianhao Wang, Jiang Xia
Abstract
act as non-contact-based antibacterial factors and together with contact-based antimicrobial peptides cause irreversible membrane destruction, cell content damage, and thermal ablation of the bacteria. Lastly, nanodot-doped peptide hydrogels combined with collagen showed complete bacterial elimination and significantly accelerated wound healing in a splint-fixed mouse infection model.
Topics & Concepts
AntimicrobialWound healingBacteriaSelf-healing hydrogelsAntimicrobial peptidesChemistryPeptideNanodotReactive oxygen speciesAntibacterial activityBiofilmMicrobiologyHeminBiophysicsBiochemistryMedicineBiologyImmunologyOrganic chemistryGeneticsHemePhysical chemistryEnzymeAntimicrobial Peptides and ActivitiesNanoplatforms for cancer theranosticsAntimicrobial agents and applications